After a serious accident aboard a Bajoran shuttle, Dr. Bashir struggles to save Vedek Bareil's life while Kai Winn concludes a peace treaty with Cardassia, putting his ethics to the ultimate test. Jake and Nog reluctantly explore the differences between Human and Ferengi cultures.

An ancient Bajoran prophecy complicates the first joint Bajoran, Cardassian, and Federation science mission: an attempt to establish a permanent communications link through the wormhole.