Erica, Father Jack and Hobbes realize that the Vs know names and addresses of The Fifth Column members and must take drastic measures to protect them. Meanwhile, Ryan finally reveals to Val that he's a Visitor, and Chad, with the camera rolling for "Prime Focus," begins the process aboard the Mothership's Medical Bay to have his aneurysm removed.

After a violent attack on someone very close to Anna, she delivers a message that the Vs don't feel safe and will be leaving; and Anna also gives a list of possible Fifth Column members to Chad, hoping he'll investigate to help in finding them. Meanwhile, Erica and the team try to track down a scientist who may have created a weapon that the Visitors are afraid of.