After Prue is accused of stealing a priceless tiara from the Auction House, she is stunned to discover Rex and Hannah are warlocks, set to destroy the power of the charmed ones. When Piper and Phoebe set out to prove Prue's innocence, Rex and Hannah blackmail them to turn over the book of shadows and their powers to them. However, their plan is foiled by a guardian angel that comes to help the sisters.

While driving, Piper's car breaks down and she ultimately gets attacked by an ancient creature called Wendigo. She ultimately gets saved by a passerby named Billy, but not before being scratched and as a result, starts to transform into a Wendigo as well. As a result, Prue and Phoebe have to find a way to save Piper before it's too late. Elsewhere, Andy teams up with an FBI agent hunting the Wendigo with disastrous results. After Prue hires Phoebe to work at the auction house, Phoebe has a vision involving a car crash and missing child.