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When a shape-shifting demon gets and ultimately opens Pandora's Box, the sisters are tasked with tracking down the Guardian of the box so all the evil that is housed in it can be put back inside.
When Zankou attempts to ambush Piper, Phoebe, and Paige in order to obtain the power of the Nexus and use it to his own advantage, little Wyatt takes matters into his own hands by shrinking Leo and Piper and hiding them in a doll house for protection while Phoebe and Paige have to deal with the demon and his henchmen. After stopping Zankou for the moment, the sisters talk Leo into becoming the new Headmaster of Magic School, hoping that he'll get used to no longer having his powers.
When a powerful sorceress casts a spell to switch bodies with Phoebe in order to attack Zankou and his followers, Phoebe is stuck in the Underworld. As a result, of the switch, Phoebe is stuck in the sorceress' body when her sisters vanquish her. Meanwhile, Paige gets her first official Whitelighter charge and tries to persuade him to use his powers as needed. After a few demon attacks at P3, Inspector Sheridan suspects that the sisters are up to something, especially after a deliveryman gets injured.