While helping Agent Brody by reading through some cold cases that Homeland Security has on hand, Billie inadvertently puts on a belt she found and is granted superhero powers that can turn the sexes against one another. As a result, she comes under the power of a power hungry female demon who plans to use Billie's new powers to gain female domination the world over. As Piper tries to book a headlining musical act to perform at P3, Paige gets a new charge that causes her to cross paths with a new love interest.

After receiving a warning from the Angel of Death that Leo is on his list of souls to collect, Piper casts a spell to make everybody look like Leo so Death can't complete his job. She then turns to the Elders and Avatars for help in keeping Leo safe, only to discover that it's Leo's destiny to die. As a result, Piper turns to the Angel of Destiny in an attempt to cut a deal to keep him alive. As Billie tracks down a lead in her attempt to locate her sister, Paige has her first date with Henry.