While Barry investigates the murders of several homeless people whose bodies are being stolen from the crime scenes, Tina reconnects with an old friend, Dr. Carl Tanner, who has recently returned to Central City to retrieve Tina's late husband's research on genetic engineering. Barry and Tina learn that Tanner is using the vagrants in his illegal experiments.

Master thief Stan Kovacs assembles a team of criminals, which the police believe intend to steal the Mask of Rasputin from the museum of natural history.