When one of J.D.'s favorite patients Harrison Marks is in dire need of a kidney transplant, J.D. takes matters into his own hands by finding his long-lost son Murray in hopes that he'll donate his kidney. Despite Dr. Cox's warning to J.D. interfere with family business, J.D. persists and complications arise. Meanwhile, Elliot is fed-up with co-workers not taking her seriously, and discovers she can get her way by flaunting her femininity with some help from Carla and Jordan.

J.D.'s ego gets in the way of his learning when Elliot, his Co-Chief Resident, continually outperforms him with their patients. Meanwhile, Turk makes light of his diabetes by inventing a guessing game of his inculin levels with the nursing staff, leaving Carla flustered. Elsewhere, the Janitor feels rejected by his secret crush Elliot when she runs off quickly from their "coffee date." Assuming his nice dress attire scared her off, he makes up a story that he was dressed to impress for his a capella band practice which leads to Elliot requesting an impromtu performance.