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Monk's hypnotic regression to his childhood begins to affect the case on which he's consulting - an actress who's disappeared, and the holes in her story when she's found after a deadly escape.
Monk's hundredth case, involving a serial killer, is covered by a TV news magazine, but while watching it he realizes that a second unknown killer was responsible for one of the murders.
Monk's Christmas spirit, or lack thereof, is challenged when he takes a case from three homeless men who believe their friend was murdered, and Leland's epiphany sends him on a mission.