Susan has her hands full with a pregnant Chloe. Benton goes to dinner with Jeanie. Carter makes a good impression on Dr. Swift, while Mark further alienates the new Chief when he decides to honor a family commitment rather than stay longer at the ER to help him. Doug turns down an offer to "celebrate" with Linda Farrell, instead getting more serious with Diane as he agrees to coach Jake's Little League team.

On a fateful Mother's Day, several staffers in the ER face possible life-changing events. Susan Lewis' sister Chloe gives birth to a beautiful - and healthy - baby girl. Things start to go wrong however when their mother Cookie - who had agreed to take in Chloe and the baby - suddenly decides she's done enough and Susan will have to take care of it. Carter turns down an offer for an ER sub-internship in the hopes that he'll get an offer in surgery. Dr. Hicks has news for him however. Benton's mother takes a turn for the worse. Carol Hathaway is overwhelmed with the final preparations as her wedding day approaches.