Gallant's sister is in town and Pratt hits it off with her. Corday is the only one that attends Romano's memorial service. Alex steals a severed finger and later goes missing, turning up at County to see Luka. Luka and Sam share a moment. Neela treats two Amish kids who were injured on a sojourn into the city.

Carter is back in Chicago and has brought Kem with him. His return to the hospital is uneventful, although there is an awkward moment when Kem meets Abby. Sam gets called to Alex's school as it seems that he was suturing his own cut. She asks Abby whether the nurses' insurance covers family therapy. Gallant discovers that his sister has been getting it on with Pratt, although she later dumps him. Pratt accidentally breaks a patient's neck while doing an unsupervised intubation. Missing Valium is found in Weaver's labcoat, although it's implied that Morris took it. Luka informs Weaver that he's leaving for the Congo in two weeks. However, he later decides to stay in Chicago indefinitely.