An unexpected visitor puts Clemente in the middle of a domestic dispute, and things don't look good. As the police sort out events, Luka, Abby and Sam try to save the victim in the aftermath of a shooting. Luka and Abby await important news about the baby. Pratt finds himself the center of unexpected attention at a fundraising event.

Note: "Many Rivers to Cross" performed by Lou Beatty, Jr.

Weaver must make a difficult choice about having hip replacement surgery when the pain interferes with her work. Ultimately she decides to go forward with it, and asks Abby to take care of Henry if something goes wrong. When Abby discovers that one of her patients has contracted meningococcemia, the E.R. is briefly quarantined. Sam treats a man who collapsed, Richard Elliott, who offers her an intriguing job. Meanwhile, Neela decides to attend a support group for military spouses. Pratt confesses to Kovač that he falsified a blood test; an infuriated Kovač suspends him for five days.