There's a new attending in the house, Dr. Victor Clemente, and he has not made a great first impression. Clemente puts the residents through their paces, alienating Pratt and infuriating the R2s. Luka spends the day with recently awakened coma patient Blaire. As Luka struggles with whether or not to tell her about her accident, Blaire tries to make sense of her flashes of memories, resulting in a tragic event. In the ER, Luka and Clemente clash over her treatment, and Luka finally tells her what happened, possibly too late. Abby visits her cancer patient, leading her to get a baseline mammogram. Dr. Dubenko's surgery goes well, and Ray meets a new girl at a rock concert.

A young girl is used as a "human shield" by her kidnapper, and both are wounded during a shoot-out with police. While Abby treats the girl, she is caught in the middle of a dispute between Clemente and Luka over the girl's care. Neela assists Luka, then Dubenko, with the kidnapper. Later, Luka and Clemente argue over style and practice, leading Luka to put his name in as a candidate for Chief of Emergency Medicine. Abby takes her anger, and need for comfort, to Luka. Gallant's leave is delayed, to Neela's dismay, and Ray gets his comeuppance from Zoe's father.