For Neela, what begins as a routine ride-along with Gates and Zadro turns into a defining day when a commercial jet and a private plane crash over Chicago. As Clemente manages the trauma in the ER, Pratt joins Neela on-scene. Luka and Abby wake up together at Luka's, but the crash soon takes them back to work, where the tension between Luka and Clemente continues. As patients flood in, Sam recalls Haleh when extra nurses are needed, and earns Eve's approval. Luka and Abby care for a patient with severe facial injuries while Pratt struggles to save a patient with a heart injury. Ray's youthful friend returns and creates a nuisance. As the day ends, Luka and Abby talk, and awkwardly decide to stay "just friends," while Neela has a welcome, and overdue, visitor.

Kerry and Pratt treat a little girl hit by a stray bullet. Luka and Ray treat a woman with cancer who makes a difficult choice. Clemente's former flame shows up. Eve's extreme response to a rude patient forces Luka to bring in the nursing supervisor. Haleh auditions singers for the Christmas party. Sam discovers the impact Steve's imprisonment has had on Alex, and takes him to visit his father. Abby shares some big news with Luka.