Weaver must make a difficult choice about having hip replacement surgery when the pain interferes with her work. Ultimately she decides to go forward with it, and asks Abby to take care of Henry if something goes wrong. When Abby discovers that one of her patients has contracted meningococcemia, the E.R. is briefly quarantined. Sam treats a man who collapsed, Richard Elliott, who offers her an intriguing job. Meanwhile, Neela decides to attend a support group for military spouses. Pratt confesses to Kovač that he falsified a blood test; an infuriated Kovač suspends him for five days.

When Luka answers a call for help, he discovers not everyone is pleased. Will he honor his commitment, or ask a colleague to step in for him? Abby and Morris wrestle with the strange case of a car crash victim. Having made a change in her life, Sam finds herself enjoying a few new perks. Neela has unexpected visitors, with even more unexpected news.