The ER must be evacuated when several workers from a chemical plant track benzene all over the floors. After Weaver is felled by the poison, Carter takes over, directing the evacuation. Dr. Corday does a ride-along with EMTs and rescues a man trapped under a building. Doug and Carol are trapped in the elevator with a sick child.

Corday tries a new experimental procedure on an Asian gentleman without permission from either the patient or a relative. Scott Anspaugh, finally released from the hospital, suffers an attack during a wall-climbing expedition with Jeanie. They discover that he will need a bone marrow transplant. Benton accidentally backs into a pedestrian at a gas station. Dr. Morgenstern makes his return to the ER, with a new outlook on life and his patients. Carter visits Chase, who has suffered brain damage from a heroin overdose.