Greene assists paramedics in treating injured children at a school bus accident. En route, Doug and Jeanie survive their own accident. Kerry stops Doug from treating Jeanie...or any other patient. Doug decides to resign and leave Chicago for the Northwest and asks Carol to come with him. She decides against it, but he leaves anyway. Carol steps down from running the clinic so that Anspaugh will keep it open. Jeanie discovers she may have contracted hepatitis. Hospital janitor Mobalage's wife is stabbed.

During a paramedic ride-along, Carter is forced to drive the ambulance while fleeing a riot scene and inadvertently runs over a teenage boy. Later, a paramedic is shot by an angry mob looking for the driver of the ambulance. Carol is despondent following Doug's departure. She later discloses that she's pregnant. Kerry is intrigued by an injured pro wrestler and his relationship with his father. Lucy tangles with an Asian family that requests their matriarch not be told of a cancerous tumor. Jeanie turns down dates with both Dr. Baker and Reggie, telling each she's seeing someone else.