Mark learns that his tumor is back and inoperable, giving him 4-5 months to live. Corday is living in a hotel, and confesses to Benton that she thinks she's left Mark. Susan cares for Mark after his first radiation treatment. Abby learns that the case against Brian has been dropped because somebody beat him up. Seeing Brian enter her building, she seeks comfort at Luka's, where he's engaged in a game of Pictionary with his friends. Jerry and Frank clash, leading to a fistfight. Chen has a stalker.

Corday, still living in the hotel, is avoiding Mark, until Ella says her first words. Elizabeth pressures Susan to tell her what her husband is hiding, and figures out her husband's fate. Romano advises her to return to Mark for the little time he has left. Chen treats a man too traumatized to speak. Mark tells the staff about his prognosis. Weaver worries about Sandy Lopez as she is reported missing in a fire. Weaver tracks her down at a bar, and the two make out. Stabbings on a college campus bring girls to the ER.