With Eric still missing, Maggie returns to town. Carter tells Abby he wants to marry her. Weaver gives Luka an ultimatum regarding his job. Chen tells Pratt about her son. Sean Simmons returns with pneumonia. Pratt, riding with the paramedics, pronounces a derelict dead, but the man is later discovered alive by Gallant in the morgue. Weaver has her purse snatched on the street by a perpetrator who later appears in the ER as a patient.

Alderman Bright returns to blackmail Weaver into treating his gay lover for syphilis (off the record, of course). Unfortunately, the man dies from an allergic reaction to penicillin and Kerry is forced to cover up her mistake. Things between Abby and Carter have cooled down following Carter's aborted marriage proposal, but they soon heat up again. Luka has a very unconventional therapy session. Romano's condition forces Anspaugh to replace him as chief of staff...with Weaver.