Even though the lab has been shut down, Dr. Vindi manages to activate the dreaded Blue Shadow Virus, infecting Ahsoka, Padmé, and many clone troopers. The plague is fatal within 48 hours. Anakin and Obi-Wan must travel to the mysterious planet, Iego, to secure the only known antidote to the sickness. Anakin and Obi-Wan arrive on the mysterious planet to find its population living in fear of a mysterious force that has been killing anything that tries to leave their world. With the help of Jaybo Hood, a clever Iegoan boy, Anakin and Obi-Wan must solve the planet's mystery before they can leave, and before everyone infected with the Separatist virus dies!

With the space blockade around Ryloth destroyed, Obi-Wan Kenobi must lead a small clone force into a droid occupied town to sabotage their anti-aircraft guns. Obi-Wan's mission is complicated when he learns the town's inhabitants are being used as living shields. A pair of clones in his platoon forges an unlikely friendship with a refugee Twi'lek girl, Numa, who's been orphaned by the war. Through their relationship with her, the clones begin to understand the real cost of the war...