Khloe invites her ex, Tristan Thompson to True's first birthday party; Khloe decides to throw Kourtney a birthday party, but Kourtney's anxiety about turning 40 threatens to ruin the celebration; Kim receives a devastating medical diagnosis that could change her life forever.

Kourtney and Scott approach the family for parenting advice, but some unwelcome input from Corey leads to a blowout argument between him and Scott. Khloe plans a wine-tasting trip to Napa to check in with Kylie and see how her sister is handling some significant life changes. The family is fed up with Kim's new intense security protocol, so they take matters into their own hands.