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A nude man is found tied to his bed, having suffocated while he was being sexually assaulted. Concurrently, a crematorium owner is found murdered. When they investigate, they discover dozens of bodies that were never cremated.
The team investigate the manufacture of lethal drugs at mobile labs, and an elderly woman is murdered at a senior home.
A mugger is found dead on the street, his neck broken. But Horatio's team has a bigger problem on their hands as during the autopsy, Alexx and Horatio realize the man was exposed to radiation. Now the team must race against time to find the man's killer before the next victim, an environmental lawyer, dies from radiation poisoning