Alexx's DNA is found throughout her neighborhood where she is suspected to be responsible for the death of a convicted child molester. The CSI team soon learns that the mindset of the neighborhood could lead to any of the community wanting the man gone. The team must find out who the real killer was to clear Alexx.

The Miami-Dade district attorney loses a highly publicized murder trial in which a husband is accused of killing his young bride and then dumping her body in a lake. However, the woman's body is recovered after the trial concludes, and the 'double jeopardy' clause precludes the husband from being tried again. Now, as the CSIs fear that justice may not be served, new evidence suggests that the husband may have actually practiced on another victim first, and Horatio believes that CSIs may be able to get the husband retried under different grounds.