A murder and kidnapping becomes personal when DNA from a crime scene reveals that Natalia's sister Anya (Natalie Morales) is one of the kidnapped women they are looking for. The team finds a safe full of photos of missing women and they must find the photographer who was using his camera to lure the unsuspecting women. This episode was based on the photographer William Richard Bradford who photographed Eva LaRue's sister.

A Marine recruiter is found dead on a civilian shooting range with various bullet holes in him, but there is no blood at the scene. The CSIs find out that the victim was dead before he was shot and that his body was pulled onto the range. As the case advances, Horatio determines the murder may be tied to the death of a marine in Iraq who was killed in combat. Natalia is shocked to learn that Nick asked Valera out and that she accepted.