Cooper, Danny and Mike are suspicious of a man who has a nearly perfect winning streak; Sam's whale brings his grandmother to the casino to play bingo; Danny gets convinced by Mike that he needs to do a "dry run" for the hospital.

Mike's mother finds out about his marriage to Piper and is upset, prompting Mike to put together a wedding ceremony, which in turn prompts Danny to formally propose to Delinda. Casey's little brother Vic shows up with plans to take ownership of the Montecito.

In the final season, only 19 episodes of the originally planned 22 episode season were filmed at the time the show was cancelled in 2008. The final episode ended with a cliffhanger with many issues left unresolved.