Denny and Alan learn Denny's "Mad Cow" has progressed to the point of actual Alzheimers; Denny finds an experimental drug that could help and the two set out to get it. Jerry and Katie represent a young woman who was admitted and then rejected from Harvard University because she took Ritalin to focus on her SAT test. After dealing with a very bored Catherine, Carl helps her sue the television networks for not broadcasting material for those over age fifty.

Denny and Alan run into trouble when they try to obtain a marriage license and are forced to defend their decision in court. Alan presents his case for Denny to receive an experimental Alzheimer's drug to the Supreme Court. Shirley and Carl deal with the last minute details before their wedding.