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Friends and enemies converge in Victorian London to await the arrival of The Witness. Cole and Railly lead their pursuers on a manhunt through time.
Cole and Railly find themselves at opposite ends of an unspeakable decision. Jones grows suspicious while Railly turns to an emotional ally for advice. All hell breaks loose during a massive fire-fight.
Cole and Railly finally learn the heart-breaking life story of the man who calls himself The Witness.
With the identity of the Witness - the engineer of the reality ending Army of the 12 Monkeys - now known, Cole and his allies must travel through different eras in history to stop him.