Jackie forces Dan to reveal some devastating news to Roseanne: he's been having an affair in California with a nurse who cared for his mother. Meanwhile, D.J. wants the job of videotaping Darlene giving birth; and Jackie must face a harsh truth about her own love life.

When a heartbroken Roseanne locks herself in her room and won't come out, her family and friends all try in their own unique way to help her get out of her funk. Friends and family try an intervention after they're unable to rouse a listless Roseanne out of bed, where she's been for four days amid piles of junk food, depressed over Dan's affair.