Turtle-X is on a rampage and it's not Cody's fault! Someone is controlling Turtle-X remotely but the question is who and why? And more importantly, will the Turtles and Cody live long enough to find out!

An old enemy from the past returns, and he wants Bishop destroyed and only the Turtles can help him. However, when Bishop is kidnapped, the Turtles learn that before he became the Global President and cleaned up his act, he did some "dirty work" for the Earth Protection Force-- poaching and gene splicing aliens. It turns out that in 2055, there was a lab accident that had catastrophic results...