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Cyber Shredder releases a virus that wipes out the Turtles' memories and brainwashes them into thinking they are his loyal Foot minions.
Serling, desperate to return to his own time, builds a makeshift Time Window. Unfortunately, he accidentally shrinks himself to five inches tall and goes on a time traveling adventure. Unfortunately, when he escapes the clutches of arguing Turtles, he is found by Wendell, an old man who has been hunting him since Serling destroyed his toy eighty years previously and wants to reproduce him.
The Cyber Shredder creates a web portal that he hopes will allow him to venture from cyberspace into the real world. The villain first tests the device by releasing all sorts of mutants and monsters from various online programs. The Turtles must take down the creatures before they tear the city apart… and shut down the web portal before Cyber Shredder is able to use it and enter into the real world!