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After recovering Jamie and Logan, the team discovers that similar events happened in 1895... and a jellyfish in Lisbon may hold the key to cure. However, a traitor from within threatens to end the mission just as it's beginning.
The team's mysterious sponsor finally reveals herself and asks for their help dealing with a burgeoning food crisis. Meanwhile, Jamie and Logan reach Caraquet and find the city in flames. However, some of the townspeople have survived and offer them sanctuary... but it's not as safe as it appears.
While Mitch probes Jackson's memories as a child, the others go to the English village of Holbreach to find property belonging to the 19th century entertainer who may have originally mutated the animals in 1895.
The danger escalates as the animal mutation moves to Phase 2, and they begin attacking infrastructure and creating deadly environmental phenomena in a bid to make the planet uninhabitable. Also, the team discovers a mutation that threatens the life of one of their own.