On a sun-scorched Brazilian island, aggressive anaconda and deadly stingray torment survivalists Whitney and Nathan, pushing both of them to their breaking point. Working together they use their hunting and fishing skills to try and make it 21 days.

When a third survivalist crashes the challenge, tension and jealousy are just as threatening as the piranha and jaguars of the Ecuadorian rainforest. Claims that there's more going on than just survival puts everyone's challenge at risk.