The first "Naked and Afraid" couple faces challenges to themselves and their relationship as they take on the relentless Guyana jungle; they must work together to battle jaguars, anacondas, caiman, and more than two-million species of insects.

Avoiding the dangers of a rushing river, two survivalists brave a vast cave system in the Colombian rainforest; trying to survive 21 days, the jungle tests them with threats including venomous fer-de-lance snakes, piranhas and biting insects.