During a Blue Train rave, a young girl dies among party goers when she starts bleeding from her eyes, nose, and mouth. The CSI's believe her to be a victim of a biological attack. The investigation is further complicated when it is revealed that Hawkes once knew the girl. Further up town, a rich playboy is found drowned in his indoor lap pool with his former maid as a suspect.

The murder of a young woman in a hospital goes undetected by the hospital staff. The victim was the driver in a drunk driving accident which killed her best friend, and she had just come out of a coma.