The leader of the Red Claw group (known herself only as Red Claw) attacks a military train and steals a viral plague, which she intends to release in Gotham if she isn't paid a ransom. Can Batman and Catwoman put aside their differences and work together to stop Red Claw before it is too late?

Batman encounters the Scarecrow and attempts to foil his scheme to burn down Gotham University, but in the process is exposed to the Scarecrow's fear gas, and is forced to face his own guilt over the death of his parents.