Cathy seeks a second opinion, causing a strain on her relationship with Dr. Todd; Sean learns about his sister's cancer while adjusting to life with a pregnant Rebecca; Adam sees a therapist against his will.

Cathy and Paul experience frustrations in bed and with the help of their new house mate Andrea, realize they need to set some patient-caregiver limits; Rebecca is put off by the newly medicated Sean; unsatisfied by his physical relationship with Mia, Adam turns to another girl, Emily.