After her open-ended escape to Costa Rica, Violet has finally returned home and to the practice. Everyone treads a little lightly around her, especially Pete and Addison who have mixed feelings about Violet's desire to reconnect with Lucas. Meanwhile Amelia butts into Sam's personal life, pointing out that he can mend hearts in the OR but can't seem to do that for himself; and Sheldon encourages Charlotte to reconcile with Cooper, while Cooper deals with a young patient who eats everything in sight.

Naomi puts Fife in a conflicted position when she begs him to help William's advanced ALS with his still experimental treatment. Meanwhile Violet and Amelia treat a woman with a brain tumor who has to choose between life or quality of life, and Sheldon decides to officially throw his hat into the ring for Charlotte's affections.