After tragedy strikes the Montgomery family, Addison goes home to Connecticut and Sam and her friends decide to join her. Meanwhile, Sheldon and Violet clash when Sheldon's death row patient confesses to a crime that his wife, one of Violet's patients, believes he didn't commit.

The doctors of Oceanside clash when an expectant mother and her husband, desperate to have children, come to them in order to harvest the eggs of their unborn, ill-fated baby; meanwhile, Amelia tries to help a friend who threatens suicide if her tests for Huntington's Disease are positive, and Fife returns to tell Naomi how he feels about her.