Amelia's drug addiction spins further out of control as she plays hooky from work with a new fling, starts writing pill prescriptions for herself, and has a run-in with the cops; Addison and Jake are at odds when they must make the impossible choice between donating their patient's organs or saving the life of her healthy, unborn baby; Violet begins working at Seaside Wellness again, and Cooper, Charlotte and Mason begin to form a family bond, much to Erica's chagrin.

Amelia makes the hard decision to enter a rehab facility, and finds strength in an 18 year-old girl, as they both go through the painful detox process. Meanwhile, Cooper's strengthening bond with his son is tested by his allegiance to a patient in need, Pete and Violet's marriage reaches a tipping point, and Addison collapses from her rigorous fertility treatments.