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After hearing a patient's chilling confession, Violet turns to Sheldon for advice. Meanwhile, Addison tries to keep her grief a secret, Cooper and Charlotte adapt to their new reality and Sam confronts Sheldon about his denial.
The doctors join together for a celebration at Addison's house and to reminisce about the past. Meanwhile, Sheldon counsels a suicidal patient who comes forward with a shocking confession.
Sheldon fears the worst when a little girl goes missing from the ER; Addison and Jake have a disagreement about one of his patients; and a new doctor joins the team at Saint Ambrose. Meanwhile, Stephanie questions Sam about his past with Addison.
Violet has to adapt to a new way of life, Sheldon tries to deal with his illness and Charlotte is given some unwelcome news.