Hank's relationship with Jill becomes strained when he gives care to an illustrator with a heart ailment. Elsewhere, Divya needs to diagnose a shy newlywed before the honeymoon can begin.

Tucker's dad tries to kick his drug habit with a rapid detox program, but Hank objects because of it's dangers; Evan tries to prove he can have a female friend; Hank finally hears from Boris, and is invited to New York; Charlie learns about Hank and Jill's relationship, but is not ready to quit trying to patch things up with Jill.