A plane crashes in Philadelphia after a passenger opens fire, and the entire team pitch in to work the disaster. With the city's main power grid affected by the crash, Megan must conduct autopsies in between blackouts, and during one of them, a body goes missing. Meanwhile, Tommy and Adam get in a serious car accident.

Megan's father's exhumation uncovers more questions about what she always believed was a suicide, and her mother suggests she examine his patient files for clues about his death and that of a patient.