Goren and Eames investigate the murder of a math student who had worked in a poker club as a card-counter. They uncover a group of computer nerds, then discover a computer gambling system with tougher suspects. The detectives learn even their own workstations are hit by the ringleader of the group (Ian Kahn).

The investigation into the murder of a crooked cop leads to a preening veterinarian and his friend, an obsessive doctor whose ex-girlfriends have all been infected with a rare disease.