Houston welcomes veterinarians Dr. Blue, Dr. Ross and Dr. Lavigne. With cases ranging from risky surgeries to diagnosing hungry chameleons, their hands are full. A car accident brings the practice to a halt as one of the doctors faces a long recovery.

While Dr. Blue & Dr. Ross help a client at their goat farm, Dr. Lavigne must save a pup with an obstruction in his intestines and a concerned family waiting. Dr. Blue & Dr. Ross compete in a cook-off to see who is the best grill master.