Dr. Blue has a crisis on his hands with a dog that chewed off her own tail, while Dr. Ross treats a reptile that might need a tail amputation. Dr. Lavigne helps Sutter Butter, a cat rescued from being thrown out of a car, and is now having seizures.

Dr. Lavigne performs a risky surgery on a loving pit bull with a record-breaking tumor; Dr. Ross examines a rescue pigeon turned pet; an aspiring vet student joins Dr. Blue at Cy-Fair; the doctors deal with a heartbreaking situation at the clinic.