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The team search for a priest in desperate need of a liver transplant who goes missing after performing last rites at the scene of a car crash.
When a school bus vanishes into thin air during it's morning route, it quickly becomes clear that the bus has been hijacked and the children riding it are being held for ransom. Meanwhile, Sam deals with the physical and emotional trauma of her recent gunshot wound, and Jack attempts to make amends with his estranged family.
When a a recently engaged woman disappears from her engagement party, the team discovers her background is riddled with frauds and scams. Meanwhile, Sam reluctantly sees a therapist to help her process recent events at work.