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When Kyle's first kidney transplant from an organ donated by his older brother fails, he gets a second chance at life when his sister Jess offers to donate one of hers.
Single mum Tracy faces a life-and-death battle with a rare and aggressive brain cancer. The programme also follows Kylie, the coordinator of the RPA team, who is revolutionising emergency stroke care.
Nurse Sharon's life is turned upside down when she's diagnosed with colorectal cancer and she faces a complex operation.