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Kane's alternative treatment seems to have worked and he is back in control of his city. Now he must remedy his public perception, even if it means making an old friend collateral damage.
Kane's moves with the housing project escalate tensions from unrest to rioting and looting. As Chicago burns, Kane secretly seeks treatment at an alternative clinic, where his past haunts him.
Kane reluctantly enters an alliance with a longtime foe on City Council, but he soon realizes that more serious measures must be undertaken to stave off bankruptcy.
This season, Kane ferociously beats back the physical symptoms of his illness with high doses of medication. But this comes at a cost -- experiencing heightened psychological manifestations of the disease. Without his longtime advisors Stone and Kitty, Kane is also forced to reconfigure his inner circle. Surrounded by strangers and without much time left, he acts quickly to protect and repair his legacy by cutting out the cancers within the political machine. But as corrupt heads roll and his list of enemies grows, Kane's virtuous actions begin to erode the very foundation of power he's worked a lifetime to build. In order to maintain it, Kane must govern as he always has - ruthlessly.