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Kane uses personal tragedy to further his agenda, poaches his nemesis's aide, Mona, and hires ambitious newcomer Ian - but will they be enough to fill the void that Stone left behind?
Tom Kane cements his mayoral legacy with a lavish ceremony celebrating the groundbreaking of the new modernized O'Hare terminals. Now Kane looks to the future, setting his sights on reviving a subsidized housing project. While his political future seems bright, Kane continues to battle for control over his disease.
Kane's increasing infatuation with his new aide Mona leads him to get swept up in her enthusiasm for a housing-redevelopment project.
This season, Kane ferociously beats back the physical symptoms of his illness with high doses of medication. But this comes at a cost -- experiencing heightened psychological manifestations of the disease. Without his longtime advisors Stone and Kitty, Kane is also forced to reconfigure his inner circle. Surrounded by strangers and without much time left, he acts quickly to protect and repair his legacy by cutting out the cancers within the political machine. But as corrupt heads roll and his list of enemies grows, Kane's virtuous actions begin to erode the very foundation of power he's worked a lifetime to build. In order to maintain it, Kane must govern as he always has - ruthlessly.