Joining Jools on the first show of a brand new series is Birmingham-born Laura Mvula, who returns to the show following her debut in 2013 with tracks from her upcoming second album, The Dreaming Room, which builds on the rich sound of her big-selling debut Sing To The Moon and sees her working with the likes of Nile Rodgers and Miles Davis collaborator John Scofield.

Jools also welcomes legendary singer-songwriter Paul Simon for a rare solo appearance as he launches his latest solo album, Stranger To Stranger, on the eve of a major American tour. He'll be performing a new song and a classic.

From East London, acclaimed British grime MC, KANO first appeared on the show back in 2007 and he returns to the Later… studio to run through tracks from his recent Top 10 album ‘Made In The Manor', his first album in six years and his fifth long player to date which has been described as "as much a love letter to his East End roots as it is a forensic portrayal of inner city England today, with just the merest hint of dark prophecy about what trouble may lie round the corner..."

Making his debut on the show is Nashville singer songwriter and guitarist Jason Isbell. A former member of alt-country band Drive By Truckers, who has been having great success since going solo in 2007 and he will be performing a couple of tracks from his recent fifth album ‘Something More Than Free', which not only went Top 20 in the UK, but saw mainstream success in the US going Top five as well as winning two Grammy awards.

Returning to the Later... with Jools studio is Florida-raised soul singer extraordinaire Charles Bradley, whose star has been on the rise since his debut album was released back in 2011 when he was in his late 60s He and his band will be playing numbers from his third album, Changes, which sees ‘The Screaming Eagle of Soul' take on Black Sabbath's 1972 classic track and transform it into a bruised, beaten-down anthem for the broken-hearted.

Completing the line-up are Boston's harmony-driven and hard-gigging Lake Street Dive who will be making their UK TV debut. Lead by vocalist Rachael Price, their new album Side Pony, develops their swing-jazz take on the 60s of Motown and The Beatles.