Some women can't cope with raising a child. A young mom commits the ultimate act of betrayal; a jealous lover plots a horrible revenge; and twins becomes twice as hard for a housewife. These Deadly Women are willing to sacrifice "Innocent Blood".

Some women expect too much from their flesh and blood. When these Deadly Women convince their closest relatives to become a party to murder, they know their families won't let them down. Blood is thicker than water, when they enlist their "Killer Kin".